Belotero is the latest innovation in injectable dermal fillers. It is a hyaluronic acid (HA) formulation to temporarily eradicate facial wrinkles and folds. Belotero works similar to other HA formulations (Restylane and Juvéderm) and also targets fine lines. This dermal filler may be injected closer to the skin surface to address fine lines.
BELOTERO FORMULATIONS
Three formulations of Belotero are available in different HA concentrations. However, the FDA only approved Belotero Balance in 2011. Belotero Soft and Intense are approved in Russia, Italy, United Kingdom, Switzerland, Austria and Germany. Each formulation targets different areas of the face or body.
- Soft (20mg/ml)
- Balance (25 mg/ml)
- Intense (25.5 mg/ml)
Outside the US, Belotero formulations are used on the hands, nose, cheekbones and lips. Botero Balance is advised for lines around the mouth stateside, but a physician may use in other areas.
This patient received Belotero to correct a fine line on her face.*
Bel0tero Balance:
- Smile Lines: used on nasolabial folds from the side of nose to corner of mouth
- Vertical Lip Lines: used on perioral lines on the top lip
- Oral Commissures: used on corners of mouth
- Marionette Lines: used on downward lines on corners of mouth
- Tear Trough: underneath the eye
HOW BELOTERO BALANCE WORKS
HA is naturally found in the body and aides in hydration of the skin. Aging, sun damage and other environmental and lifestyle factors reduce production of HA. Belotero injections therefore replace the lost HA, which adds volume back to face. HA binds with water to plump wrinkles and folds temporarily, usually from six months to a year.
The formulation is a transparent gel injected into areas with wrinkles and folds. Its plumping and voluminous effects smooth the face. A study by Merz Aesthetics, its distributor, reveals that most patients need two injections to reach maximum skin smoothing benefits. When the efficacy fades, Belotero is naturally eliminated from the body.
This patient had Belotero to address his crow’s feet.
This patient had Belotero to address her forehead wrinkles and frown lines.
NUANCES OF THE FORMULATION
All three HA formulations are cross-linked to create thicker, longer lasting injectables. Belotero slightly differs because its structure involves Cohesive Polydensified Matrix technology. It is a monophasic compound rather than particulate suspension.
It makes it more lightweight and elastic, which allows injections closer to the surface. With the suspensions, they are prone to clumping if injected this way.
As with all injectables, side effects may include swelling at the injection site, mild irritation, bruising, itching and tenderness. Always consult with a board certified physician to determine if Belotero is appropriate.